BDBM317632 Syntheses of Compounds in Table 1A::US9624205, 1

SMILES COc1nn(C)c(C)c1CNC(=O)c1c(C)n(C(C)C2CCOCC2)c2ccccc12

InChI Key InChIKey=SNKJBPOZCATWLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317632   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM317632(US9624205, 1 | Syntheses of Compounds in Table 1A)
Affinity DataIC50: 5.00E+4nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM317632(US9624205, 1 | Syntheses of Compounds in Table 1A)
Affinity DataIC50: 2.80E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent