BDBM317482 4-(4-((1s,4s)-4-hydroxy-4- methylcyclohexyloxy)-5-(4- (methylcarbamoyl)phenyl)-7H- pyrrolo[2,3-d]pyrimidin-2- ylamino)-3-methoxy-N-(1- methylazetidin-3-yl)benzamide::US9623028, Compound 349

SMILES CNC(=O)c1ccc(cc1)-c1c[nH]c2nc(Nc3ccc(cc3OC)C(=O)NC3CN(C)C3)nc(OC3CC[C@@](C)(O)CC3)c12

InChI Key InChIKey=MCYPGAGHAANYON-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317482   

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317482(US9623028, Compound 349 | 4-(4-((1s,4s)-4-hydroxy-...)
Affinity DataIC50: 1.15nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317482(US9623028, Compound 349 | 4-(4-((1s,4s)-4-hydroxy-...)
Affinity DataIC50: 59.3nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317482(US9623028, Compound 349 | 4-(4-((1s,4s)-4-hydroxy-...)
Affinity DataIC50: 1.43nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent