BDBM317475 3-cyano-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4- (tetrahydro-2H-pyran-4-yloxy)- 7H-pyrrolo[2,3-d]pyrimidin-2- ylamino)benzamide::US9623028, Compound 171

SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(c1)C#N

InChI Key InChIKey=CCGBGSFDXIBQHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317475   

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317475(US9623028, Compound 171 | 3-cyano-N-methyl-4-(5-(2...)
Affinity DataIC50: 1.47nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317475(US9623028, Compound 171 | 3-cyano-N-methyl-4-(5-(2...)
Affinity DataIC50: 82.8nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317475(US9623028, Compound 171 | 3-cyano-N-methyl-4-(5-(2...)
Affinity DataIC50: 2.32nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent