BDBM317472 N,3-dimethyl-4-(5-(2- methylbenzo[d]oxazol-6-yl)-4- (tetrahydro-2H-pyran-4-yloxy)- 7H-pyrrolo[2,3-d]pyrimidin-2- ylamino)benzamide::US9623028, Compound 145

SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(C)c1

InChI Key InChIKey=YDGTUAFFLKCKEE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317472   

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317472(US9623028, Compound 145 | N,3-dimethyl-4-(5-(2- me...)
Affinity DataIC50: 2.45nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317472(US9623028, Compound 145 | N,3-dimethyl-4-(5-(2- me...)
Affinity DataIC50: 220nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317472(US9623028, Compound 145 | N,3-dimethyl-4-(5-(2- me...)
Affinity DataIC50: 40.1nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent