BDBM31682 imidazole-dioxolane, 32

SMILES FC[C@@H]1CO[C@@](CCc2ccc(Cl)cc2)(Cn2ccnc2)O1

InChI Key InChIKey=UDVNHSKNWZLJCD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31682   

TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 1.20E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 4.40E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 3.60E+3nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed