BDBM31666 imidazole-dioxolane, 18

SMILES Clc1ccc(CC[C@@]2(Cn3ccnc3)OC[C@@H](CSc3cccc(Br)c3)O2)cc1

InChI Key InChIKey=TYSVOWQYRQTDSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31666   

TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31666(imidazole-dioxolane, 18)
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31666(imidazole-dioxolane, 18)
Affinity DataIC50: 2.20E+4nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed