BDBM315568 US10172858, Table 2.65::US9828378, # 65

SMILES CC(=O)N1CCC(CC1)n1nc(-c2cc3ccc(O)cc3[nH]2)c2c(N)ncnc12

InChI Key InChIKey=NLSRIQGXBVAKNW-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 315568   

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 10nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 50nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 25nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 25nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

TargetCytosolic arginine sensor for mTORC1 subunit 1(Human)
Intellikine

US Patent
LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 10nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent

LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 50nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent

LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent

LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 25nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent

LigandPNGBDBM315568(US10172858, Table 2.65 | US9828378, # 65)
Affinity DataIC50: 25nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent