BDBM315563 US10172858, Table 2.60::US9828378, # 60

SMILES Nc1ncnc2n(nc(-c3cc4ccc(O)cc4[nH]3)c12)C1CCOCC1

InChI Key InChIKey=FBNMOHXNDJQJMI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 315563   

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandPNGBDBM315563(US10172858, Table 2.60 | US9828378, # 60)
Affinity DataIC50: 100nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM315563(US10172858, Table 2.60 | US9828378, # 60)
Affinity DataIC50: 500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM315563(US10172858, Table 2.60 | US9828378, # 60)
Affinity DataIC50: 500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM315563(US10172858, Table 2.60 | US9828378, # 60)
Affinity DataIC50: 100nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytosolic arginine sensor for mTORC1 subunit 1(Human)
Intellikine

US Patent
LigandPNGBDBM315563(US10172858, Table 2.60 | US9828378, # 60)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM315563(US10172858, Table 2.60 | US9828378, # 60)
Affinity DataIC50: 500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM315563(US10172858, Table 2.60 | US9828378, # 60)
Affinity DataIC50: 500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM315563(US10172858, Table 2.60 | US9828378, # 60)
Affinity DataIC50: 100nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent