BDBM315522 US10172858, Table 2.18::US9828378, # 18

SMILES COc1ccc2[nH]c(cc2n1)-c1nn(C(C)C)c2ncnc(N)c12

InChI Key InChIKey=UAGRJFZSCZVFST-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 315522   

TargetSerine/threonine-protein kinase mTOR(Human)
Intellikine

US Patent
LigandPNGBDBM315522(US10172858, Table 2.18 | US9828378, # 18)
Affinity DataIC50: 500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

LigandPNGBDBM315522(US10172858, Table 2.18 | US9828378, # 18)
Affinity DataIC50: 500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

TargetCytosolic arginine sensor for mTORC1 subunit 1(Human)
Intellikine

US Patent
LigandPNGBDBM315522(US10172858, Table 2.18 | US9828378, # 18)
Affinity DataIC50: 500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent

LigandPNGBDBM315522(US10172858, Table 2.18 | US9828378, # 18)
Affinity DataIC50: 10nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent