BDBM31531 Substituted Benzamide Derivative, 2::med.21724, Compound 163

SMILES C[C@@H](NC(=O)c1cc(CN)ccc1C)c1cccc2ccccc12

InChI Key InChIKey=BIKTWHWUIKAJAT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31531   

TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
Purdue University

LigandPNGBDBM31531(Substituted Benzamide Derivative, 2 | med.21724, C...)
Affinity DataIC50: 460nMpH: 7.5 T: 2°CAssay Description:IC50 values for all inhibitors were determined using a 96-well plate based assay. Reactions were performed in buffer containing RLRGG-AMC, 2% DMSO, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
University of Bonn

LigandPNGBDBM31531(Substituted Benzamide Derivative, 2 | med.21724, C...)
Affinity DataIC50: 460nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Purdue University

Curated by ChEMBL
LigandPNGBDBM31531(Substituted Benzamide Derivative, 2 | med.21724, C...)
Affinity DataIC50: 620nMAssay Description:Inhibition of SARS-CoV-1 papain-like proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

Curated by ChEMBL
LigandPNGBDBM31531(Substituted Benzamide Derivative, 2 | med.21724, C...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SARS-CoV-2 papain-like proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed