BDBM314867 (−) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-fluorophenyl](cyclopentyl)acetyl}amino)-2-methylphenyl]propanoic acid::US10172814, Example 44

SMILES Cc1c(CCC(O)=O)cccc1NC(=O)C(C1CCCC1)c1ccc(c(F)c1)-c1cncc(Cl)c1

InChI Key InChIKey=OZUBHMWSFYBJDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 314867   

TargetProstaglandin G/H synthase 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM314867((−) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-fluor...)
Affinity DataIC50: 18nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM314867((−) 3-[3-({[4-(5-Chloropyridin-3-yl)-3-fluor...)
Affinity DataIC50: 17.6nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent