BDBM314843 (−) (R) 3-[3-({[4-(5-Chloro-6-methylpyridin-3-yl)phenyl](cyclopentyl)acetyl}amino)-2-methylphenyl]propanoic acid::US10172814, Example 26

SMILES Cc1ncc(cc1Cl)-c1ccc(cc1)[C@@H](C1CCCC1)C(=O)Nc1cccc(CCC(O)=O)c1C

InChI Key InChIKey=LFOCEOFBNPVEJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314843   

TargetProstaglandin G/H synthase 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM314843((−) (R) 3-[3-({[4-(5-Chloro-6-methylpyridin-...)
Affinity DataIC50: 15.6nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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