BDBM314143 3-{[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]amino}pyridine-4-carboxylic acid; 3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-ylmethyl]amino}pyridine-4-carboxylic acid::US10179769, Example 47::US10807956, Example 47::US11214542, Example 47::US11639333, Example 47::US9611221, Example 47::US9725441, Example 47::US9828343, Example 47

SMILES OC(=O)c1ccncc1NC[C@H]1CCCc2ccccc12

InChI Key InChIKey=DGPKTIKFLWFZTL-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 314143   

TargetLysine-specific demethylase 5A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 550nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 100nMAssay Description:Jarid1A: The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 100nMAssay Description:Jarid1B: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction condit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM314143(US10179769, Example 47 | 3-{[(1S)-1,2,3,4-tetrahyd...)
Affinity DataIC50: 550nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2022
Entry Details
Go to US Patent