BDBM313801 US10167292, Example 45

SMILES Cc1nnn2CCN(c3ccc(Cl)cc3)c3cc(ccc3-c12)C(=O)NOCCO

InChI Key InChIKey=VHRAOPOVGCSADO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 313801   

TargetBromodomain-containing protein 2 [91-163](Human)
Catalyst Therapeutics

US Patent
LigandPNGBDBM313801(US10167292, Example 45)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
Catalyst Therapeutics

US Patent
LigandPNGBDBM313801(US10167292, Example 45)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Catalyst Therapeutics

US Patent
LigandPNGBDBM313801(US10167292, Example 45)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBromodomain-containing protein 4 [368-440](Human)
Catalyst Therapeutics

US Patent
LigandPNGBDBM313801(US10167292, Example 45)
Affinity DataIC50: 100nMAssay Description:BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...More data for this Ligand-Target Pair
In DepthDetails
US Patent