BDBM313754 US10167282, Compound TBAP-05

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(n1)-c1ccnc(O)c1

InChI Key InChIKey=VUNDVBODCIFXGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313754   

TargetSerine/threonine-protein kinase B-raf [416-766,V600E](Human)
Cancer Research Technology

US Patent
LigandPNGBDBM313754(US10167282, Compound TBAP-05)
Affinity DataIC50: 390nMAssay Description:V600EBRAF was generated by infection of SF9 insect cells cultured in SF-900 II medium (Invitrogen, Paisley, Scotland) with a baculovirus containing f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [416-766,V600E](Human)
Cancer Research Technology

US Patent
LigandPNGBDBM313754(US10167282, Compound TBAP-05)
Affinity DataIC50: 450nMAssay Description:Mutant BRAF WM266.4 Cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent