BDBM313688 N-(3-(6-((1- ethylpiperidin-4- yl)oxy)-5-(tetrahydro- 2H-pyran-4- yl)pyridazin-3-yl)-4- methylphenyl)-2- (trifluoromethyl) isonicotinamide::US10167279, Example 314

SMILES CCN1CCC(CC1)Oc1nnc(cc1C1CCOCC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=KOACOQKHCPGWQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313688   

LigandPNGBDBM313688(US10167279, Example 314 | N-(3-(6-((1- ethylpiperi...)
Affinity DataIC50: 60nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
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US Patent