BDBM313486 N-(3-(5-(3- (fluoromethyl)oxetan-3- yl)-6-methoxypyridin-3- yl)-4-methylphenyl)-2- (trifluoromethyl)isonicotin- amide::US10167279, Example 105
SMILES COc1ncc(cc1C1(CF)COC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C
InChI Key InChIKey=LMKSNXQADYFDKA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 313486
Affinity DataIC50: 91.5nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
Affinity DataIC50: 323nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair