BDBM313400 N-(3-(6-ethoxy-5-(3- methyloxetan-3- yl)pyridin-3-yl)-4- methylphenyl)-6- (trifluoromethyl)pyridazine- 4-carboxamide::US10167279, Example 67

SMILES CCOc1ncc(cc1C1(C)COC1)-c1cc(NC(=O)c2cnnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=BYRIYFLSQKIKLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313400   

LigandPNGBDBM313400(N-(3-(6-ethoxy-5-(3- methyloxetan-3- yl)pyridin-3-...)
Affinity DataIC50: 78nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
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LigandPNGBDBM313400(N-(3-(6-ethoxy-5-(3- methyloxetan-3- yl)pyridin-3-...)
Affinity DataIC50: 304nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent