BDBM313203 US9616064, Compound 1af

SMILES Nc1nccc(Nc2ccccc2)n1

InChI Key InChIKey=RFRREALVLUCVCA-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 313203   

TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM313203(US9616064, Compound 1af)
Affinity DataIC50: 5.53E+4nMAssay Description:The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM313203(US9616064, Compound 1af)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
Go to US Patent

TargetB-cell lymphoma 6 protein(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM313203(US9616064, Compound 1af)
Affinity DataKd:  3.00E+6nMAssay Description:Binding affinity to captured wild-type human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed