BDBM31286 benzodiazepinedione, 2

SMILES OC(=O)[C@H](N1[C@H](c2ccc(Cl)cc2)C(=O)Nc2ccc(I)cc2C1=O)c1ccc(Cl)cc1

InChI Key InChIKey=HQEQUYKKMMKSSX-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31286   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31286(benzodiazepinedione, 2)
Affinity DataKd:  4.80E+3nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31286(benzodiazepinedione, 2)
Affinity DataKd:  4.80E+3nMAssay Description:Displacement of fluorescein-labeled p53 peptide from HDM2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed