BDBM311783 5-(2,7-Bis(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-7-chloroindolin-2-one::US10155769, Example 21

SMILES FC(F)(F)c1nc2c(-c3cc4CC(=O)Nc4c(Cl)c3)c(ccn2n1)C(F)(F)F

InChI Key InChIKey=WADNTVQMSDGRNQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311783   

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM311783(US10155769, Example 21 | 5-(2,7-Bis(trifluoromethy...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
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