BDBM311769 7-(Azetidin-1-yl)-8-(7-methyl-1H-indazol-5-yl)-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine::US10155769, Example 7

SMILES Cc1cc(cc2cn[nH]c12)-c1c(ccn2nc(nc12)C(F)(F)F)N1CCC1

InChI Key InChIKey=BUSMMEKEWJWVMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311769   

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM311769(US10155769, Example 7 | 7-(Azetidin-1-yl)-8-(7-met...)
Affinity DataIC50: 0.316nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent