BDBM311512 CHEM-US-00232::US10155764, Example 87

SMILES C[C@H](Nc1nn(C)c(=O)c2cccnc12)[C@@H](N(C)C)c1ccc(cc1)C(=O)OCc1ccccc1

InChI Key InChIKey=BIGOMLUWBGNKQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311512   

TargetHistone acetyltransferase KAT2B [719-832](Human)
Genentech

US Patent
LigandPNGBDBM311512(US10155764, Example 87 | CHEM-US-00232)
Affinity DataIC50: 29nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In DepthDetails
US Patent