BDBM311444 CHEM-US-00141::US10155764, Example 32::US10155764, Example 32A::US10155764, Example 32B

SMILES CN(C)C1CN(CCC1Nc1nn(C)c(=O)c2cccnc12)c1ccc(Cl)cc1

InChI Key InChIKey=UGPZFEUGECMRRH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 311444   

TargetHistone acetyltransferase KAT2B [719-832](Human)
Genentech

US Patent
LigandPNGBDBM311444(US10155764, Example 32 | US10155764, Example 32A |...)
Affinity DataIC50: 140nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT2B [719-832](Human)
Genentech

US Patent
LigandPNGBDBM311444(US10155764, Example 32 | US10155764, Example 32A |...)
Affinity DataIC50: 150nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone acetyltransferase KAT2B [719-832](Human)
Genentech

US Patent
LigandPNGBDBM311444(US10155764, Example 32 | US10155764, Example 32A |...)
Affinity DataIC50: 69nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In DepthDetails
US Patent