BDBM311438 CHEM-US-00135::US10155764, Example 26

SMILES CN(C)C(CNc1nn(C)c(=O)c2ccccc12)c1ccccc1F

InChI Key InChIKey=NHHODRQTZBHNSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311438   

TargetHistone acetyltransferase KAT2B [719-832](Human)
Genentech

US Patent
LigandPNGBDBM311438(US10155764, Example 26 | CHEM-US-00135)
Affinity DataIC50: 110nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In DepthDetails
US Patent