BDBM311332 (S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluorophenyl)pyridin-2-yl)acetamide::BDBM406207::US10155760, Example 189::US9902722, Example 189

SMILES CC(C)C[C@](C)(N)COc1ncc(cc1Cl)-c1ccnc2cc(F)cc(F)c12

InChI Key InChIKey=BTDNQMGJQOYVOY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 311332   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311332((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...)
Affinity DataIC50: 0.490nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311332((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...)
Affinity DataIC50: 0.490nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311332((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...)
Affinity DataIC50: 0.490nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details
Go to US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311332((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...)
Affinity DataIC50: 0.490nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311332((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...)
Affinity DataIC50: 1.20nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311332((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...)
Affinity DataIC50: 0.490nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
Go to US Patent