BDBM310101 (S)-2-chloro-N-(1-((3-ethylphenyl)sulfonyl)-3-methyl-2,3-dihydro-1H-pyrido-[2,3-b][1,4]oxazin-7-yl)-6-fluorobenzamide ::US10377768, Compound 15::US9657033, Compound 15

SMILES CCc1cccc(c1)S(=O)(=O)N1C[C@H](C)Oc2ncc(NC(=O)c3c(F)cccc3Cl)cc12

InChI Key InChIKey=LFBQTKSEHKLABK-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 310101   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310101(US9657033, Compound 15 | (S)-2-chloro-N-(1-((3-eth...)
Affinity DataEC50:  31nMAssay Description:Recombinant,HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310101(US9657033, Compound 15 | (S)-2-chloro-N-(1-((3-eth...)
Affinity DataEC50:  10nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310101(US9657033, Compound 15 | (S)-2-chloro-N-(1-((3-eth...)
Affinity DataEC50:  31nMAssay Description:Recombinant, HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310101(US9657033, Compound 15 | (S)-2-chloro-N-(1-((3-eth...)
Affinity DataEC50:  10nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent