BDBM310087 2-chloro-6-fluoro-N-[1-(3-trifluoromethylbenzenesulfonyl)-1H-pyrazolo[4,3-b]pyridin-6-yl]benzamide ::US10377768, Compound 1::US9657033, Compound 1

SMILES Fc1cccc(Cl)c1C(=O)Nc1cnc2cnn(c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=GQCLNPMDLGCICZ-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 310087   

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310087(US9657033, Compound 1 | 2-chloro-6-fluoro-N-[1-(3-...)
Affinity DataEC50:  1.88E+3nMAssay Description:Recombinant,HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310087(US9657033, Compound 1 | 2-chloro-6-fluoro-N-[1-(3-...)
Affinity DataEC50:  25nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310087(US9657033, Compound 1 | 2-chloro-6-fluoro-N-[1-(3-...)
Affinity DataEC50:  1.88E+3nMAssay Description:Recombinant, HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM310087(US9657033, Compound 1 | 2-chloro-6-fluoro-N-[1-(3-...)
Affinity DataEC50:  25nMAssay Description:HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...More data for this Ligand-Target Pair
In DepthDetails
US Patent