BDBM309967 US9656996, Compound 34

SMILES COc1ncc(cc1NS(C)(=O)=O)-c1nc(nc2c(OC3CCC(CC3)N3CCCCC3)cc(F)cc12)N1CCOCC1

InChI Key InChIKey=PGHUYIUIFKALBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309967   

TargetTumor necrosis factor(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM309967(US9656996, Compound 34)
Affinity DataIC50: 66nMAssay Description:1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS.2. The compound was formulated in 100% DMSO in a concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
Go to US Patent