BDBM30993 Ajmalicine::MLS000111555::Raubasine::SMR000107477::cid_251561

SMILES COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12

InChI Key InChIKey=GRTOGORTSDXSFK-UHFFFAOYSA-N

Data  19 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 30993   

Target5-hydroxytryptamine receptor 1A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataEC50:  9.90E+4nMpH: 7.4 T: 2°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetAlpha-2C adrenergic receptor(OK)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  0.660nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2C adrenergic receptor(OK)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2B adrenergic receptor(Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2C adrenergic receptor(OK)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  1.71nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  6.40nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor(Pig)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2B adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  14.5nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2B adrenergic receptor(Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  31.2nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2B adrenergic receptor(Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  46nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  47.6nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  289nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2B adrenergic receptor(Rabbit)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  376nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2B adrenergic receptor(Rabbit)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  429nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  653nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM30993(Ajmalicine | MLS000111555 | SMR000107477 | Raubasi...)
Affinity DataKi:  1.47E+3nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed