BDBM309469 (2R,4S)-5-(3′-Chloro-biphenyl-4-yl)-4-[(3-hydroxy-isoxazole-5-carbonyl)-amino]-2-methyl-pentanoic acid::US9603819, Example 49-1

SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)C(\O)=C\C(O)=N)C(O)=O

InChI Key InChIKey=NXKMMJWYSKJXAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309469   

TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM309469(US9603819, Example 49-1 | (2R,4S)-5-(3′-Chlo...)
Affinity DataIC50: 0.0400nMAssay Description:The activity of a compound according to the present invention can be assessed by the following in vitro & in vivo methods and/or by the following in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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