BDBM308052 (S)-2-(1H-benzo[d]imidazol- 5-yl)-3-(3,4- dimethoxyphenyl)isoindolin- 1-one::US9650362, 142

SMILES COc1ccc(cc1OC)[C@@H]1N(C(=O)c2ccccc12)c1ccc2[nH]cnc2c1

InChI Key InChIKey=ICKMOIBSQQCIKY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 308052   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM308052(US9650362, 142 | (S)-2-(1H-benzo[d]imidazol- 5-yl)...)
Affinity DataIC50: 297nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM308052(US9650362, 142 | (S)-2-(1H-benzo[d]imidazol- 5-yl)...)
Affinity DataKi:  53.5nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In DepthDetails
US Patent