BDBM308047 (S)-1-(1H-1,3-benzodiazol- 5-yl)-5-(4- biphenyl)imidazolidin- 2-one::US9650362, 43

SMILES O=C1NC[C@@H](N1c1ccc2[nH]cnc2c1)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=QYCCTMGDALJSAQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 308047   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM308047(US9650362, 43 | (S)-1-(1H-1,3-benzodiazol- 5-yl)-5...)
Affinity DataIC50: 254nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandPNGBDBM308047(US9650362, 43 | (S)-1-(1H-1,3-benzodiazol- 5-yl)-5...)
Affinity DataKi:  40.8nMAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30° C. QC activity was evaluated fluorometrical...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent