BDBM307699 US9650336, Example 2

SMILES CO[C@H]1CC[C@]2(Cc3ccc(cc3C22C=C(F)C(N)=N2)-c2cncnc2)CC1

InChI Key InChIKey=XCPNTAGKJZPLCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307699   

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307699(US9650336, Example 2)
Affinity DataIC50: 1.97E+3nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent