BDBM307517 US10150740, Example 13

SMILES COc1cc-2c(CN(CC(C)C)n3cc(C(O)=O)c(=O)cc-23)cc1OCCC[N+]#[C-]

InChI Key InChIKey=SGQIRWOYPPQGGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307517   

TargetGenome polyprotein(HCV)
Hoffmann-La Roche

US Patent
LigandPNGBDBM307517(US10150740, Example 13)
Affinity DataIC50: 110nMAssay Description:HepG2.2.15 cells (Acs et al. Proc Natl Acad Sci USA, 84, (1987), 4641-4), a constitutively HBV-expressing cell line were cultured in DMEM+Glutamax-I ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
Go to US Patent