BDBM307516 US10150740, Example 12

SMILES COc1cc-2c(CN(CC(C)C)n3cc(C(O)=O)c(=O)cc-23)cc1OCCCCC(O)=O

InChI Key InChIKey=CAZSNQPRLXQZPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307516   

TargetGenome polyprotein(HCV)
Hoffmann-La Roche

US Patent
LigandPNGBDBM307516(US10150740, Example 12)
Affinity DataIC50: 9.43E+3nMAssay Description:HepG2.2.15 cells (Acs et al. Proc Natl Acad Sci USA, 84, (1987), 4641-4), a constitutively HBV-expressing cell line were cultured in DMEM+Glutamax-I ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
Go to US Patent