BDBM3071 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 38::2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one::6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL301612::PD 166285 analog

SMILES Cn1c2nc(Nc3ccccc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key InChIKey=MACKJBHSMLAAGO-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 3071   

TargetPlatelet-derived growth factor receptor beta(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 400nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 460nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 20nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 260nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 330nMAssay Description:Inhibitory concentration of compound against mouse Platelet-derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Chicken)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 24nMAssay Description:Inhibition of chicken c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of checkpoint kinase Wee1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3071(2-anilino-6-(2,6-dichlorophenyl)-8-methylpyrido[2,...)
Affinity DataIC50: 24nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed