BDBM304039 2-[2-(2-Methoxyphenyl)-1H-benzimidazol-5-yl]-5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazine::US10138245, Example 41

SMILES COc1ccccc1-c1nc2cc(ccc2[nH]1)-c1nc2c(C)ncc(C)n2n1

InChI Key InChIKey=CYZRRJJJSPMKOX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304039   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Celon Pharma

US Patent

LigandBDBM304039(2-[2-(2-Methoxyphenyl)-1H-benzimidazol-5-yl]-5,8-d...)Copy SMILESCopy InChI

Affinity DataIC50: 19.5nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/30/2019
Entry Details
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