BDBM304038 5,8-Dimethyl-2-[2-(pyridin-2-yl)-1H-benzimidazol-5-yl][1,2,4]triazolo[1,5-a]pyrazine::US10138245, Example 40

SMILES Cc1cnc(C)c2nc(nn12)-c1ccc2[nH]c(nc2c1)-c1ccccn1

InChI Key InChIKey=CQPLWGHMXBOGJC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304038   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Celon Pharma

US Patent

LigandBDBM304038(5,8-Dimethyl-2-[2-(pyridin-2-yl)-1H-benzimidazol-5...)Copy SMILESCopy InChI

Affinity DataIC50: 63nMAssay Description:Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/30/2019
Entry Details
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