BDBM303415 US10138222, Example 144

SMILES Cc1ccc(cc1-c1cnn(c1)-c1cncc(NC(=O)C2CC2)c1)C(=O)NC1CC1

InChI Key InChIKey=SXRVTCATJCOUEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303415   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303415(US10138222, Example 144)
Affinity DataIC50: 2.90nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent