BDBM3027 3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::3-(3-aminophenyl)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 28

SMILES Nc1cccc(c1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12

InChI Key InChIKey=WXPDCELKHNMODS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3027   

TargetEpidermal growth factor receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3027(3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50: 5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3027(3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50: 3.09E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3027(3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
Novartis Pharmaceuticals

LigandPNGBDBM3027(3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50: 1.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3027(3-(3-Aminophenyl)-4-((3-chlorophenyl)amino)-1H-pyr...)
Affinity DataIC50: 680nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed