BDBM302092 US9598415, 8
SMILES CC[C@H](C)n1c2nc(ncc2nc(NCc2ccc(cn2)S(=O)(=O)CC)c1=O)-c1c(OC)ncnc1C1CC1
InChI Key InChIKey=DCSACVSUKUQBSN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 302092
Affinity DataIC50: 290nMAssay Description:A nuclear receptor transactivation assay is performed to quantitate the ability of test compounds to inhibit RORγ transactivation of a luciferas...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Antagonist activity at GAL4 DBD-fused human RORgamma LBD expressed in pGL4.3 luc2P/GAL4UAS/hygro and pBIND transfected HEK293 cells assessed as inhib...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at RORgamma in human PBMC assessed as reduction in anti-CD3/IL-23 stimulated IL-17 level measured after 3 days by MSD assayMore data for this Ligand-Target Pair