BDBM301983 Ethyl 2-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl)-4-methylthiazole-5-carboxylate::US9598401, Example 39

SMILES CCOC(=O)c1sc(nc1C)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1

InChI Key InChIKey=MYKQYEXOLDAZQF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301983   

Target5-hydroxytryptamine receptor 1A(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM301983(Ethyl 2-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperaz...)
Affinity DataKi:  0.790nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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