BDBM3017 3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 18::4-N-(3-chlorophenyl)-3-N-[4-(dimethylamino)phenyl]-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine

SMILES CN(C)c1ccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)cc1

InChI Key InChIKey=DBMNQXNYFIEZLF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3017   

TargetEpidermal growth factor receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3017(3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophe...)
Affinity DataIC50: 29nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3017(3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophe...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3017(3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophe...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Bovine)
Novartis Pharmaceuticals

LigandPNGBDBM3017(3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophe...)
Affinity DataIC50: 2.90E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3017(3-((4-(Dimethylamino)phenyl)amino)-4-((3-chlorophe...)
Affinity DataIC50: 350nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed