BDBM3013 3-((3-Methoxyphenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 14::4-N-(3-chlorophenyl)-3-N-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine

SMILES COc1cccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)c1

InChI Key InChIKey=ABEGFBRZNZWQBS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3013   

TargetEpidermal growth factor receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3013(4-N-(3-chlorophenyl)-3-N-(3-methoxyphenyl)-1H-pyra...)
Affinity DataIC50: 8nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3013(4-N-(3-chlorophenyl)-3-N-(3-methoxyphenyl)-1H-pyra...)
Affinity DataIC50: 3.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3013(4-N-(3-chlorophenyl)-3-N-(3-methoxyphenyl)-1H-pyra...)
Affinity DataIC50: 7.80E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Bovine)
Novartis Pharmaceuticals

LigandPNGBDBM3013(4-N-(3-chlorophenyl)-3-N-(3-methoxyphenyl)-1H-pyra...)
Affinity DataIC50: 4.70E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3013(4-N-(3-chlorophenyl)-3-N-(3-methoxyphenyl)-1H-pyra...)
Affinity DataIC50: 4.30E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed