BDBM3009 3-((3-Chlorophenyl)amino)-4-((3-bromophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 10::4-N-(3-bromophenyl)-3-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine

SMILES Clc1cccc(Nc2[nH]nc3ncnc(Nc4cccc(Br)c4)c23)c1

InChI Key InChIKey=JUKRBPQFJFOIDS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3009   

TargetProtein kinase C alpha type(Bovine)
Novartis Pharmaceuticals

LigandPNGBDBM3009(4-N-(3-bromophenyl)-3-N-(3-chlorophenyl)-1H-pyrazo...)
Affinity DataIC50: 3.80E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3009(4-N-(3-bromophenyl)-3-N-(3-chlorophenyl)-1H-pyrazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3009(4-N-(3-bromophenyl)-3-N-(3-chlorophenyl)-1H-pyrazo...)
Affinity DataIC50: 130nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3009(4-N-(3-bromophenyl)-3-N-(3-chlorophenyl)-1H-pyrazo...)
Affinity DataIC50: 1.36E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2005
Entry Details Article
PubMed