BDBM300890 (3R)-3-(6-((3-(3-(2- Methoxyethoxy)-2- methylphenyl) benzo[b]thiophen-5- yl)methoxy)pyridin-3-yl) hex-4-ynoic acid::US10131648, Compound 88::US10195178, Compound 88::US9790198, Compound 88

SMILES COCCOc1cccc(-c2csc3ccc(COc4ccc(cn4)[C@H](CC(O)=O)C#CC)cc23)c1C

InChI Key InChIKey=YCLNDYASFVMVKG-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300890   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300890((3R)-3-(6-((3-(3-(2- Methoxyethoxy)-2- methylpheny...)
Affinity DataEC50:  8nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300890((3R)-3-(6-((3-(3-(2- Methoxyethoxy)-2- methylpheny...)
Affinity DataEC50:  8nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300890((3R)-3-(6-((3-(3-(2- Methoxyethoxy)-2- methylpheny...)
Affinity DataEC50:  8nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent