BDBM300245 N-methoxy-N-methyl-3-[2-(6- methyl-2-pyridyl)ethynyl]- 3a,4,5,6a- tetrahydropyrrolo[3,2- d]isoxazole-6-carboxamide::US9593127, Example 19

SMILES CON(C)C(=O)N1CCC2C1ON=C2C#Cc1cccc(C)n1

InChI Key InChIKey=KTZMKLPZODWRCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300245   

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandPNGBDBM300245(N-methoxy-N-methyl-3-[2-(6- methyl-2-pyridyl)ethyn...)
Affinity DataIC50: 239nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
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Date in BDB:
3/15/2019
Entry Details
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