BDBM300244 US9593127, Example 18::[3-[2-(6-methyl-2- pyridyl)ethynyl]-3a,4,5,6a- tetrahydropyrrolo[3,2- d]isoxazol-6-yl]-morpholino- methanone

SMILES Cc1cccc(n1)C#CC1=NOC2C1CCN2C(=O)N1CCOCC1

InChI Key InChIKey=DKPFNIBTTCJRNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300244   

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandPNGBDBM300244([3-[2-(6-methyl-2- pyridyl)ethynyl]-3a,4,5,6a- tet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
Go to US Patent