BDBM300233 3-[2-(3-chlorophenyl)ethynyl]- N,N-dimethyl-3a,4,5,6a- tetrahydropyrrolo[3,2- d]isoxazole-6-carboxamide::US9593127, Example 7

SMILES CN(C)C(=O)N1CCC2C1ON=C2C#Cc1cccc(Cl)c1

InChI Key InChIKey=CSJNTIZKMUYMPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300233   

TargetMetabotropic glutamate receptor 5(Human)
Recordati Ireland

US Patent
LigandPNGBDBM300233(3-[2-(3-chlorophenyl)ethynyl]- N,N-dimethyl-3a,4,5...)
Affinity DataIC50: 59.2nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
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Date in BDB:
3/15/2019
Entry Details
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